Recent and Important Publications

  • My research interests span interventional cardiology, coronary physiology, refractory angina, coronary microvascular disease and the mechanical complications of myocardial infarction.

    Below is a selection of publications reflecting these areas of work. A full and regularly updated publication list is available through my Google Scholar profile.

    Post-infarction ventricular septal defect

    Post-infarction ventricular septal defect: percutaneous or surgical management in the UK national registry
    Giblett JP, Matetic A, Jenkins D, et al.
    European Heart Journal. 2022;43(48):5020–5032.

    This national study examined contemporary surgical and percutaneous treatment of post-infarction ventricular septal defect across the UK. The work formed part of a larger international research programme into this rare but serious complication of myocardial infarction.

    Transcatheter treatment of post-infarction ventricular septal defects
    Giblett JP, Jenkins DP, Calvert PA.
    Heart. 2020;106(12):878–884.

    A review of the role of transcatheter closure in the management of post-infarction ventricular septal defects.

    Percutaneous transcatheter closure of post-infarction ventricular septal defect: an alternative to surgical intervention
    Cadogan D, Daghem M, Snosi M, Williams LK, Weir-McCall J, Calvert PA, Giblett JP.
    Interventional Cardiology: Reviews, Research, Resources. 2023;18.

    Coronary intervention and coronary physiology

    The role of glucagon-like peptide-1 loading on periprocedural myocardial infarction during elective PCI: the GOLD-PCI study
    Giblett JP, Clarke SJ, Zhao TX, et al.
    American Heart Journal. 2019;215:41–51.

    A randomised, double-blind, placebo-controlled clinical trial investigating whether GLP-1 could reduce myocardial injury during elective coronary intervention.

    Glucagon-like peptide-1-mediated cardioprotection does not reduce right ventricular stunning and cumulative ischaemic dysfunction after coronary balloon occlusion
    Giblett JP, Axell RG, White PA, et al.
    JACC: Basic to Translational Science. 2019;4(2):222–233.

    A human mechanistic study examining myocardial responses to controlled coronary ischaemia.

    GLP-1 is a coronary artery-specific vasodilator in humans
    Clarke SJ, Giblett JP, Yang L, et al.
    Journal of the American Heart Association. 2018;7.

    Anatomical plaque and vessel characteristics are associated with haemodynamic indices including fractional flow reserve and coronary flow reserve
    Brown AJ, Giblett JP, Bennett MR, West NEJ, Hoole SP.
    International Journal of Cardiology. 2017;248:92–96.

    Angina and coronary microvascular disease

    The coronary microcirculation re-explored: pathophysiological insights and clinical implications
    Elamin A, Abdimalik M, Abdelrahim M, et al.
    European Cardiology Review. 2025;20.

    A contemporary review of coronary microvascular physiology, disease mechanisms, diagnosis and treatment.

    Coronary sinus reducer implantation for refractory angina: a national audit of UK practice
    Cheng K, et al.
    Heart. 2026.

    An analysis of UK experience with coronary sinus reducer implantation in patients with refractory angina.

    Coronary disease and revascularisation

    Complete revascularisation following acute myocardial infarction: a contemporary review
    Gonnah A, Darke N, Mullen L, Hung JD, Sandhu K, Giblett JP.
    Interventional Cardiology: Reviews, Research, Resources. 2025;20.

    A review of contemporary evidence and clinical decision-making around complete revascularisation following acute myocardial infarction.

    Implantation of bioresorbable vascular scaffolds following acute coronary syndrome is associated with reduced early neointimal growth and strut coverage
    Giblett JP, Brown AJ, Keevil H, Jaworski C, Hoole SP, West NEJ.
    EuroIntervention. 2016;12(6):724–733.

    Structural and other interventional cardiology

    Transcatheter versus surgical management of paravalvular leak: a single-centre experience with purpose-specific occluders
    Giblett JP, Jara T, MacCarthy T, et al.
    JACC: Cardiovascular Interventions. 2022;15(12):1293–1295.

    Percutaneous management of paravalvular leaks
    Giblett JP, Williams LK, Moorjani N, Calvert PA.
    Heart. 2022;108(13):1005–1011.

    Percutaneous management of paravalvular leaks
    Giblett JP, Rana BS, Shapiro LM, Calvert PA.
    Nature Reviews Cardiology. 2019.

    Patent foramen ovale closure: state of the art
    Giblett JP, Williams LK, Kyranis S, Shapiro LM, Calvert PA.
    Interventional Cardiology Review. 2020;15(3).

    Full publication record

    For a complete and up-to-date list of publications, citations and research activity, please see my Google Scholar profile.